What is this disease? How is it
caused? Can it be cured? Dr. Vivek Jain answers the most frequently asked
questions on Leucoderma.
What exactly is Leucoderma?
Strictly speaking, Leucoderma is
not a medical term, though it has come to mean any white/light coloured
skin patch. Very broadly, white patches can be acquired or may be present
at birth. Again, both acquired and congenital skin patches can result from
hordes of reasons. While congenital patches are not of much importance
- since a majority of them are birthmarks anyway, the disease wherein acquired
patches develop is generally referred to as Leucoderma (or Leucoderma in
medical terms). Other acquired white patches usually follow some preceding
What causes Leucoderma?
Despite advanced research, medicine is still trying to figure out the exact cause (leave alone the most appropriate treatment!) of Leucoderma. There are numerous theories as to what could cause this disease, of which three have been widely accepted.
The first theory is one of mistaken identity. The immune system mistakes the pigment cells for foreign bodies and destroys them. The second theory states that certain chemical agents destroy the pigment generating cells, while the third theory states that the cells are destroyed due to chemical exposure.
Whatever the cause, the course of
the disease is certain - and that is the destruction of pigment cells.
But why do only certain areas of the body get affected? Why doesn't this
disease affect the entire body? After all, pigment cells are present throughout
the body. It's still a mystery.
Is Leucoderma hereditary?
Children of parents where one or
both have Leucoderma are only at a fraction of a higher risk than the general
population. Even the general population is at a risk of 1-2 %. This means
that even with no family history for generations, any normal and fit person
too stands a chance of 1-2 % of developing Leucoderma (practically for
no reason at all).
Why are Leucoderma spots white?
White patches need not always spell doom. Only a fraction of them could be the dreaded Leucoderma. And that too, a majority of the cases are amenable to medical management.
Can Leucoderma be caused by consuming contrasting food items like fish/onions with milk?
Nothing can be further from the truth.
This is a myth with absolutely no scientific basis. How this old grandma's
tale started is still a matter of speculation. A point that should further
strengthen the belief that diet has absolutely nothing to do with Leucoderma
is that no dietary restrictions of any kind are imposed on a Leucoderma
patient. Vitamin-C rich foods, which were once thought to promote the disease
process, are no longer restricted either because of their proven and beneficial role as antioxidants.
How is it confirmed whether a white patch is Leucoderma?
The white patch will in all probability be Leucoderma if it:
There is NO cure for Leucoderma, and any doctor promising a cure is sure to be a quack! At the most, the patches can be coloured to match the skin, but this will not stop new patches from occurring.
What if two people with this disease get married to each other or if one person marries a Leucoderma patient or someone with a family history of Leucoderma?
If both parents have Leucoderma,
it does increase the child's chance of getting it, but only nominally.
Very often, children of parents with Leucoderma have no trace of the disease.
If the disease is 'full-blown' in both the parents, the children could
have a maximum 25% chance of acquiring it. As of now there is no test,
genetic or prenatal, that will help decide the fate of the child in this
What are Albinos?
Unlike Leucoderma patients whose
skin gets white in patches, Albinos have universal white skin, white hair,
white eyebrows, and even white iris. Albinos are those few people who are
born with dysfunctional pigment cells that do not produce colour at all.
On the other hand Leucoderma patients have pigment cells that were once
functional, but later destroyed due to some reason or the other.
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