Register | Login
Login
Sign in with:
---------- OR ----------
Create Account | Login
Create account
As a Member You Can:
  • Join clubs to discuss your interests
  • Connect with people like you
  • Share information, seek advice, get support

   
parenting
in Mumbai (change city)
Select City
  • All
  • Delhi
  • New Delhi
  • Gurgaon
  • Noida
  • Mumbai
  • Pune
  • Banglore
  • Hyderabad
  • Ghaziabad
  • Chandigarh
  • Ahmedabad
  • Kolkata
  • Chennai
  • Coimbatore
  • Jaipur
 
Fertility Issues Topics..

 
You are here : home > Fertility Issues > Problems in Getting Pregnant > In Vitro Fertilisation

In Vitro Fertilisation


While modern technology is very good at making embryos in the laboratory, we still cannot control the implantation process. We do not know which embryo will become a baby - and this can be very frustrating, for both patients and doctors.However, you need to remember that embryo implantation consists of a series of phases in which the embryo has to appose and attach itself to the maternal endometrium and invade into it.

The enigma of embryo implantation - why doesn't every embryo become a baby?

While modern technology is very good at making embryos in the laboratory, we still cannot control the implantation process. We do not know which embryo will become a baby - and this can be very frustrating, for both patients and doctors! 

Many patients who do not get pregnant after an embryo transfer start believing that their bodies are defective, and that they have "rejected" the embryo. They feel that if they failed to become pregnant even after the doctor transferred 3-4 good quality embryos, that they are flawed. However, you need to remember that embryo implantation is a very complex process, which consists of a series of phases in which the embryo has to appose and attach itself to the maternal endometrium and invade into it. 

First, the embryo has to undergo further development, till it reaches the blastocyst stage, when it hatches from its shell, known as the zona

The hatched blastocyst then needs to implant in the endometrium. This occurs during the period of time known as the implantation window. 

Apposition, or orientation of the embryo (which is at the blastocyst stage at this time) within the cavity of the uterus, starts when the cavity has become minimal due to the suction of endometrial fluid by pynopods (small protrusions found on the surface membrane of the cells lining the uterus). 

Adhesion of the blastocyst is a progressive phenomenon that ties the embryo to the endometrium and is the primary event initiating invasion. Many molecules, such as cytokines, growth factors and cell adhesion proteins called integrins play an important role in this complex process during which the blastocyst and maternal endometrium must undergo an exquisite dialogue. 

Invasion is a self-controlled proteolytic process that allows the embryonic trophoblast to penetrate deep into the maternal decidua and to invade the endometrial spiral arteries by producing chemicals called proteinases. How implantation is regulated and brought about remains an enigma, but we need to remember that the implantation process is surprisingly inefficient in humans - Nature is not always very competent! After IVF, it's only about 10%, which means that only 10% of embryos implant successfully to become a baby. The responsibility for this low efficiency has to be shared between the embryo the endometrium, as well as a defective embryo-endometrium dialogue. We still cannot successfully predict which patient will get pregnant after embryo transfer. We now know that one of the major reasons for failure of the embryo to implant is a genetically abnormal embryo. Basic research on implantation is of great interest today, because embryonic implantation is the major limiting factor in allowing pregnancy after ART, but we still need to learn a lot about this "black hole" in our knowledge, before we can learn to control it ! Some clinics attribute failure of the embryos to implant to immunological problems - and even offer "treatment" for this, but there is no proof to support this theory. 

Remember, embryo implantation is a complex process, which you cannot influence by your diet or physical activity, so there is no need for you to blame yourself if the embryos do not implant.

You may also be interested in:

Smart Parenting
(45214 views)
Fussy Eating Habits
(21214 views)
Help with Conceiving
(27934 views)
Cancel
Save Edit
parenting
Notifications
61 Comments
Sort by Newest

.10 months ago
IVF means In-Vitro Fertilization. Couple should consider IVF without much delay if

IUI cycles failed 2-4 times
Wife has blocked Fallopian tubes
Premature failure of ovaries
Advanced female age – over 38 years old
Severe endometriosis
Husband has low sperm count or low motility

IVF cycle in snapshot

Ovaries are stimulated with hormones to produce more eggs
Eggs released from ovaries are extracted by laparoscopy
Under high power microscope, egg is injected with a good quality sperm from husband
Fertilised egg is grown inside an incubator under controlled micro-environment
In 2-3 days it grows into an embryo, which is transferred into uterus

Read more: *****.com
1
 
 
 
.
Reply
Homecheck.4 years ago
Special offer from Homecheck- Buy Male fertility supplements with best discount offer..
These male fertility dietary supplements boost fertility as well as improve overall reproductive system. These highly effective male fertility supplements maximize male fertility by improving quality and quantity of sperm.
Contact us - 011-23357326, 09560506177 Email - home.check.new@gmail.com
visit - http://www.home-check.net.in/male-fertility
 
 
 
.
Reply
Homecheck.4 years ago
Special offer from Homecheck- Buy Male fertility supplements with best discount offer..
These male fertility dietary supplements boost fertility as well as improve overall reproductive system. These highly effective male fertility supplements maximize male fertility by improving quality and quantity of sperm.
Contact us - 011-23357326, 09560506177 Email - home.check.new@gmail.com
visit - http://www.home-check.net.in/male-fertility
 
 
 
.
Reply
Homecheck.4 years ago
Special offer from Homecheck- Buy Male fertility supplements with best discount offer..
These male fertility dietary supplements boost fertility as well as improve overall reproductive system. These highly effective male fertility supplements maximize male fertility by improving quality and quantity of sperm.
Contact us - 011-23357326, 09560506177 Email - home.check.new@gmail.com
visit - http://www.home-check.net.in/male-fertility
 
 
 
.
Reply
Homecheck.4 years ago
Special offer from Homecheck- Buy Male fertility supplements with best discount offer..
These male fertility dietary supplements boost fertility as well as improve overall reproductive system. These highly effective male fertility supplements maximize male fertility by improving quality and quantity of sperm.
Contact us - 011-23357326, 09560506177 Email - home.check.new@gmail.com
visit - http://www.home-check.net.in/male-fertility
 
 
 
.
Reply
Homecheck.4 years ago
Special offer from Homecheck- Buy Male fertility supplements with best discount offer..
These male fertility dietary supplements boost fertility as well as improve overall reproductive system. These highly effective male fertility supplements maximize male fertility by improving quality and quantity of sperm.
Contact us - 011-23357326, 09560506177 Email - home.check.new@gmail.com
visit - http://www.home-check.net.in/male-fertility
 
 
 
.
Reply
Homecheck.4 years ago
Special offer from Homecheck- Buy Male fertility supplements with best discount offer..
These male fertility dietary supplements boost fertility as well as improve overall reproductive system. These highly effective male fertility supplements maximize male fertility by improving quality and quantity of sperm.
Contact us - 011-23357326, 09560506177 Email - home.check.new@gmail.com
visit - http://www.home-check.net.in/male-fertility
 
 
 
.
Reply
Homecheck.4 years ago
Special offer from Homecheck- Buy Male fertility supplements with best discount offer..
These male fertility dietary supplements boost fertility as well as improve overall reproductive system. These highly effective male fertility supplements maximize male fertility by improving quality and quantity of sperm.
Contact us - 011-23357326, 09560506177 Email - home.check.new@gmail.com
visit - http://www.home-check.net.in/male-fertility
 
 
 
.
Reply
Homecheck.4 years ago
Special offer from Homecheck- Buy Male fertility supplements with best discount offer..
These male fertility dietary supplements boost fertility as well as improve overall reproductive system. These highly effective male fertility supplements maximize male fertility by improving quality and quantity of sperm.
Contact us - 011-23357326, 09560506177 Email - home.check.new@gmail.com
visit - http://www.home-check.net.in/male-fertility
 
 
 
.
Reply
load more comments
Back to Previous Page   |   More on Fertility Issues Index

 
 


All tips on Problems In Getting Pregnant
You ever wanted in one place.
No need to go anywhere else. No spam.

*No spam only genuine emails
Follow us on:




Featured Articles - Infertility | Baby Development | Health and Fitness | How to Get Pregnant | Parenting Advice | Weight Loss | Pregnancy Advice | Name Numerology
Baby - Baby Photo Contest | Lucky Names | Lucky Birthdates | Horoscopes | Chinese Calendar | Compatibility Test | Fun Zone
Parenting - Message Boards | Planning a Baby | Pregnancy | Parents of Babies | Baby Names | Baby Name Poll | Birth Announcements | Parenting Quiz
Family - Cooking Club | Love & Relationships | Beauty Tips | Kids Weight Calculator | Recipe Maker
General - Calorie Counter | Personality Quiz | Love Signs | Compatibility Quiz
Home | Site Map | Privacy Policy | Comments or Suggestions | Indiaparenting News Articles | Contact Us | Advertise with Us | | RSS
Copyright (c) 1999 - 2017 India Parenting Pvt. Ltd.